Check the labels of any medicines or food products you use to make sure they do not contain alcohol or propylene glycol. Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop taking the medicine and call your doctor right away if you have neurologic side effects more likely to occur while taking metronidazole long term :. Metronidazole can cause life-threatening liver problems in people with Cockayne syndrome. If you have this condition, stop taking metronidazole and contact your doctor if you have signs of liver failure --nausea, stomach pain upper right side , dark urine, clay-colored stools, or jaundice yellowing of the skin or eyes.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Sometimes it is not safe to use certain medications at the same time.
Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. This list is not complete. Other drugs may affect metronidazole, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient.
Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Symptoms associated with mixing Flagyl and alcohol include:. Symptoms can occur even if you drink several hours after taking the medication, or even the next day. Flagyl is usually taken over the course of 10 days, and it is best to wait a minimum of 72 hours after taking the last dose before consuming alcohol.
Note: Some over-the-counter medications, such as cough and cold medicines, contain alcohol. The warning label printed with each prescription of Flagyl cautions against taking such medications, as well as other products that contain even the smallest amount of alcohol including mouthwash. One of the most significant indicators of addiction is the inability to convince yourself to stop doing something even when you know the results could be hazardous, even fatal.
Because Flagyl is typically taken for only a short amount of time, the longest you will likely need to stop drinking in order to avoid adverse effects is about two weeks or so. If you, or a loved one, find it difficult or impossible not to drink even during this brief interlude, it may be time to consider whether your alcohol use has become an addiction.
Parties and holidays, of course, can make it harder to resist. To make sure the tablets, liquid or suppositories are safe for you, tell your doctor if you: have had an allergic reaction to metronidazole or any other medicines in the past are pregnant or breastfeeding have liver problems are having dialysis feel you will not be able to stop drinking alcohol while using metronidazole To make sure the external cream or gel is safe for you, tell your doctor if you: have had an allergic reaction to metronidazole or any other medicines including any creams or ointments in the past are pregnant or breastfeeding To make sure the vaginal gel is safe for you, tell your doctor if you: have had an allergic reaction to metronidazole or any other medicines in the past are pregnant or breastfeeding have liver problems feel you will not be able to stop drinking alcohol while using metronidazole think you may have vaginal thrush.
How long should I take it for? Important Carry on taking this medicine until you have finished the course, even if you feel better. What if I forget to take it? What if I take too much? How to put it on Put a thin layer of cream or gel onto the area you're treating and rub it in very gently.
How long should I use it for? Important Carry on using this medicine until you have finished the course, even if you feel better. What if I forget to use it? What if I use too much? How to use it Follow the instructions that come in the packaging along with your medicine. Do not have sex while using the vaginal gel. If you accidentally use too much gel it's unlikely to harm you. Talk to your pharmacist or doctor if you're worried. Common side effects of tablets, liquid, suppositories or vaginal gel Keep taking the medicine, but talk to your doctor or pharmacist if these side effects bother you or do not go away: feeling sick nausea being sick vomiting or diarrhoea metallic taste in your mouth or a furry tongue Serious side effects of tablets, liquid, suppositories or vaginal gel Serious side effects are rare and happen in less than 1 in 1, people.
Serious allergic reaction In rare cases, it's possible to have a serious allergic reaction anaphylaxis to metronidazole. Information: You can report any suspected side effect using the Yellow Card safety scheme.
Visit Yellow Card for further information. What to do about: feeling sick nausea — stick to simple meals and do not eat rich or spicy food.
You should always try to take your metronidazole after a meal or snack. Take small, frequent sips if you are being sick. Signs of dehydration include peeing less than usual or having dark, strong-smelling pee. If your diarrhoea and vomiting continues for more than 24 hours contact your doctor for advice.
Do not take any other medicines to treat diarrhoea or vomiting without speaking to a pharmacist or doctor. If your tongue is very furry, this could be a sign of thrush — ask your pharmacist or doctor for advice. Non-urgent advice: Tell your doctor if you're:. Tell your doctor before you start taking metronidazole tablets, suppositories, liquid or vaginal gel if you're taking these medicines : a blood thinner called warfarin lithium used to treat some types of mental health problem disulfiram used to help people stay off alcohol phenytoin or phenobarbitone used to treat epilepsy ciclosporin used to dampen the immune system fluorouracil or busulfan used to treat some types of cancer any medicines that you take as a liquid, in case these contain alcohol Mixing metronidazole with herbal remedies and supplements There are no known problems with taking herbal remedies and supplements alongside metronidazole.
Important: Medicine safety Tell your doctor or pharmacist if you're taking any other medicines, including herbal medicines, vitamins or supplements.
How does metronidazole work? How long does it take to work? What if I don't get better? Will it stop my contraception working? Will it give me thrush? Ask your pharmacist or doctor for advice if this happens to you. Will it reduce my fertility? Can I drive or ride a bike? Metronidazole does not usually affect you being able to drive or cycle. Can I drink alcohol with it? Is there any food or drink I need to avoid?
Otherwise you can eat and drink normally. Taking Flagyl and drinking alcohol can have similar effects, which may be more noticeable when a person combines the two. People may experience the following side effects of Flagyl:. While some people do not experience the effects of combining alcohol and Flagyl, doctors and pharmacists recommend avoiding alcohol as a precaution.
This can reduce the risk of Flagyl causing side effects. Since Flagyl can cause seizures, people with a history of seizures should be especially careful to avoid alcohol while taking the antibiotic. When a person consumes alcohol, the body breaks it down in two steps. First, it breaks alcohol into a compound called acetaldehyde.
Acetaldehyde is toxic and responsible for the unwanted effects of alcohol. Next, the body reduces acetaldehyde to acetate. It does this with an enzyme called aldehyde dehydrogenase. Flagyl blocks the effects of this enzyme. As a result, a person on Flagyl cannot fully digest alcohol, and drinking can cause the toxic acetaldehyde to build up in the bloodstream. Because of this, people who drink alcohol while taking Flagyl may experience a disulfiram-like reaction.
Disulfiram is a drug that helps treat alcohol addiction. Mixing disulfiram and alcohol has health effects that discourage people from drinking. A disulfiram-like reaction occurs when alcohol interacts similarly with a drug other than disulfiram, such as Flagyl. When a person combines Flagyl and alcohol, their disulfiram-like reaction may be mild to moderate and include:. Authors of a case study report the death of a year-old woman who consumed alcohol while taking metronidazole.
Reactions do not occur in all people. This may suggest that the risk of developing a disulfiram-like reaction to Flagyl and alcohol varies from person to person.
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